Diproteverine
Diproteverine (BRL 40015) is an oral activity calcium channel blocker. Diproteverine embryonic toxicity. Diproteverine also shows antianginal properties.
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- No. CAS: 69373-95-1
- Fòrmula: C26H35NO4
- Peso molecular:425.56
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Sprague-Dawley virgin female rats[1]
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Dosage:40, 80, 160, 320 mg/kg
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Administration:P.o.; daily for 10 days
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Result:Induced embryonic deaths, significantly increased incidence of fetuses showing an unusual pattern of digital, tail, heart, and vertebral abnormalities.
Chemical Information
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No. CAS 69373-95-1
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Peso molecular 425.56
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Fòrmula C26H35NO4
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SMILES
CC(C)OC1=CC2=C(CCN=C2CC3=CC=C(C(OCC)=C3)OCC)C=C1OC(C)C
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Synonyms
BRL 40015
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Ridings JE, et al. Prenatal toxicity studies in rats and rabbits with the calcium channel blocker diproteverine. Reprod Toxicol. 1996 Jan-Feb;10(1):43-9. [Content Brief]
[2]. Lacroix P, et al. Diproteverine (BRL 40015): a new type of calcium antagonist with potential antianginal properties. Eur J Pharmacol. 1991 Jan 17;192(3):317-27. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)