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United States

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Referencia número: HY-168144

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DJ-53

DJ-53 (compund 68) is an orally active phenylquinoline-based soluble epoxide hydrolase inhibitor.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₂₆H₂₂F₃N₃O₄
Peso molecular:497.47

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

DJ-53 Chemical Structure

Tamaño

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

DJ-53 (compund 68) is an orally active phenylquinoline-based soluble epoxide hydrolase inhibitor^[1].

IC₅₀ & Target

Epoxide Hydrolase^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
HEK-293T	IC₅₀	>200 μM Compound: 68; DJ-53	Cytotoxicity against HEK293T cells incubated for 48 hrs by CCK8 assay Cytotoxicity against HEK293T cells incubated for 48 hrs by CCK8 assay	[PMID: 39361006]
HepG2	IC₅₀	>200 μM Compound: 68; DJ-53	Cytotoxicity against human HepG2 cells incubated for 48 hrs by CCK8 assay Cytotoxicity against human HepG2 cells incubated for 48 hrs by CCK8 assay	[PMID: 39361006]

Chemical Information

Peso molecular 497.47
Fòrmula C₂₆H₂₂F₃N₃O₄
SMILES

COC1=CC(C2=CC3=CC=C(C=C3N=C2)NC(NCC4=CC=C(C=C4)OC(F)(F)F)=O)=CC(OC)=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Ding J, et al. Discovery of Orally Active Phenylquinoline-Based Soluble Epoxide Hydrolase Inhibitors with Anti-Inflammatory and Analgesic Activity. J Med Chem. 2024 Oct 24;67(20):18412-18447. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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