L-689560
Based on 1 Customer Validation
L-689560 is a potent N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. L-689560 is widely used as a radiolabeled ligand in binding studies and used for study the roles of NMDA receptors in normal neurological processes as well as in diseases.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.29%
- No. CAS: 139051-78-8
- Fòrmula: C17H15Cl2N3O3
- Peso molecular:380.23
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Ver todos los productos específicos de isoformas iGluR
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Actividad biológica
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NMDA Receptor |
L-689560 is a 2-carboxytetrahydroquinoline antagonist[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Adult male Sprague-Dawley (SD) rats middle cerebral artery occlusion (MCAO) model[1]
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Dosage:1 mg/kg
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Administration:IP
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Result:Significantly reduced the neuroprotective effect of glycine after glycine receptors.
Chemical Information
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No. CAS 139051-78-8
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Appearance Solid
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Peso molecular 380.23
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Fòrmula C17H15Cl2N3O3
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Color White to off-white
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SMILES
O=C([C@@H]1NC2=C(C(Cl)=CC(Cl)=C2)[C@@H](NC(NC3=CC=CC=C3)=O)C1)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L-689560 Related Classifications
HY-101178 Related Classifications
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