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Referencia número: HY-169950

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NMDA agonist 1

NMDA agonist 1 (compound 42d) is a potent NMDA agonist with a K_i value of 96 nM. NMDA agonist 1 acts as a partial agonist of the GluN1/GluN2B complex with an EC₅₀ value of 78 nM.

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No. CAS: 2576586-47-3
Fòrmula: C₁₂H₁₃N₃O₃S
Peso molecular:279.31

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

NMDA agonist 1 Chemical Structure

No. CAS: 2576586-47-3

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Descripciòn

NMDA agonist 1 (compound 42d) is a potent NMDA agonist with a K_i value of 96 nM. NMDA agonist 1 acts as a partial agonist of the GluN1/GluN2B complex with an EC₅₀ value of 78 nM^[1].

IC₅₀ & Target^[1]

NMDA Receptor

96 nM (Ki)

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Chemical Information

No. CAS 2576586-47-3
Peso molecular 279.31
Fòrmula C₁₂H₁₃N₃O₃S
SMILES

O=C([C@@H](CNC(C1=CC2=NC=CC(C)=C2S1)=O)N)O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Ascic E, et al. Advancements in NMDA Receptor-Targeted Antidepressants: From d-Cycloserine Discovery to Preclinical Efficacy of Lu AF90103. J Med Chem. 2024 Nov 28;67(22):20135-20155. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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NMDA agonist 1

Ver todos los productos específicos de isoformas iGluR

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NMDA agonist 1 Related Classifications

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