(+)-Coclaurine
(+)-Coclaurine ((+)-(R)-Coclaurine), benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine has anti-aging activity.
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- No. CAS: 2196-60-3
- Fòrmula: C17H19NO3
- Peso molecular:285.34
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| H9 | EC50 |
0.8 μg/mL
Compound: R-coclaurine
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Inhibition of HIV replication in H9 cells
Inhibition of HIV replication in H9 cells
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[PMID: 18316190] |
| H9 | EC50 |
2.8 μM
Compound: 121
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Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA
Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA
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[PMID: 20187635] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2196-60-3
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Peso molecular 285.34
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Fòrmula C17H19NO3
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SMILES
OC(C=C1)=CC=C1C[C@@H]2C3=CC(O)=C(OC)C=C3CCN2
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Synonyms
(+)-(R)-Coclaurine; (R)-Coclaurine; d-Coclaurine
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Siva S Panda, et al. Protective effects of Aporosa octandra bark extract against D-galactose induced cognitive impairment and oxidative stress in mice. Heliyon. 2018 Nov 30;4(11):e00951. [Content Brief]
[2]. H Watanabe, et al. Effects of d-coclaurine and d-reticuline, benzyltetrahydroisoquinoline alkaloids, on levels of 3,4-dihydroxyphenylacetic acid and homovanillic acid in the mouse striatum. J Pharmacobiodyn. 1983 Oct;6(10):793-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(+)-Coclaurine Related Classifications
HY-N2550 Related Classifications
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