(R)-Ifosfamide
(R)-Ifosfamide is a chemotherapeutic agent primarily used in the treatment of aggressive tumors such as rhabdomyosarcoma, exhibiting alkylating activity that interferes with DNA replication. (R)-Ifosfamide is an isomeric derivative of the DNA alkylating agent Ifosfamide (HY-17419).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 66849-34-1
- Fòrmula: C7H15Cl2N2O2P
- Peso molecular:261.09
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Chemical Information
-
No. CAS 66849-34-1
-
Peso molecular 261.09
-
Fòrmula C7H15Cl2N2O2P
-
SMILES
ClCCN1[P@](OCCC1)(NCCCl)=O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
-
PCNA Immunodetection Proliferation Assay
PCNA immunodetection measures proliferative activity by detecting proliferating cell nuclear antigen, a nuclear protein associated with DNA polymerase δ function and DNA replication. The assay readout is the proportion of PCNA-positive nuclei among total counted cells, but PCNA labeling is not identical to BrdU labeling because PCNA can mark late G1/early S-associated replication competence and may persist beyond active DNA synthesis depending on fixation and extraction conditions.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)