Selcopintide acetate
Based on 1 Customer Validation
Selcopintide (Cpne7-DP) acetate consists of a synthetic peptide corresponding to the 10 amino acid residue 344-353 fragment of the hCPNE7 protein. Selcopintide acetate highly reproduces the in vitro effects of CPNE7 by upregulating odontoblast marker genes, DSPP, and Nestin. Selcopintide acetate promotes dentin regeneration in dentinal defects of various degrees and that the regenerated hard tissue demonstrates the characteristics of true dentin.
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- Pureza: 99.63%
- Fòrmula: C64H109N21O17
- Peso molecular:1444.68
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Almacenamiento:
Stored under nitrogen, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Selcopintide (Cpne7-DP) acetate directly penetrates odontoblastic cell (MDPC-23 cells) [1].
Selcopintide (1, 10 μg) acetate increases dspp promoter activity in a dose-dependent manner[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Immunocompromised mice (NIH-bg-nu-xid)[1]
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Dosage:10 µg
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Administration:Subcutaneous transplantation in a 0.5% fibrin gel
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Result:Promotes dentin-like tissue formation.
Promotes the regeneration of tubular dentin and dentinal tubule occlusion in shallow and deep cavity models.
Chemical Information
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Appearance Solid
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Peso molecular 1444.68
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Fòrmula C64H109N21O17
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Color White to off-white
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Synonyms
Cpne7-DP acetate
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Sequence
Lys-Tyr-Lys-Gln-Lys-Arg-Arg-Ser-Tyr-Lys
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Sequence Shortening
KYKQKRRSYK
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Stored under nitrogen, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvente y solubilidad
H2O : 100 mg/mL (69.22 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.6922 mL | 3.4610 mL | 6.9219 mL | 17.3049 mL |
| 5 mM | 0.1384 mL | 0.6922 mL | 1.3844 mL | 3.4610 mL | |
| 10 mM | 0.0692 mL | 0.3461 mL | 0.6922 mL | 1.7305 mL | |
| 15 mM | 0.0461 mL | 0.2307 mL | 0.4615 mL | 1.1537 mL | |
| 20 mM | 0.0346 mL | 0.1730 mL | 0.3461 mL | 0.8652 mL | |
| 25 mM | 0.0277 mL | 0.1384 mL | 0.2769 mL | 0.6922 mL | |
| 30 mM | 0.0231 mL | 0.1154 mL | 0.2307 mL | 0.5768 mL | |
| 40 mM | 0.0173 mL | 0.0865 mL | 0.1730 mL | 0.4326 mL | |
| 50 mM | 0.0138 mL | 0.0692 mL | 0.1384 mL | 0.3461 mL | |
| 60 mM | 0.0115 mL | 0.0577 mL | 0.1154 mL | 0.2884 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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