SPK-843
SPK-843 is an antifungal agent. SPK-843 shows inhibitory activity against A. fumigatus MF-13, A. flavus TIMM 0057, and A. niger TIMM 2814 with MICs of 0.5 μg/mL, 0.25 μg/mL, and 0.0625 μg/mL, respectively. SPK-843 exhibits dose-dependent efficacy in murine models of pulmonary aspergillosis. SPK-843 can be used for the research of related fungal infections.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 143483-67-4
- Fòrmula: C67H103N5O19
- Peso molecular:1282.56
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 143483-67-4
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Peso molecular 1282.56
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Fòrmula C67H103N5O19
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SMILES
O=C([C@H]1[C@@](C[C@H](/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@]([C@@H](C)CCC(O)CC(C2=CC=C(NC)C=C2)=O)([H])OC3=O)O[C@@](O[C@H](C)[C@@H](O)[C@@H]4NC(CN(C)C)=O)([H])[C@H]4O)([H])O[C@](O)(C[C@H](C[C@H](C[C@H](C[C@H](CC(C[C@H](C3)O)=O)O)O)O)O)C[C@@H]1O)NCCN(C)C
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Synonyms
SPA-S-753 free base
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)