STING modulator-5
STING modulator-5 (compound 38) is a STING modulator with a pIC50 value of 9.5. STING modulator-5 antagonizes peripheral blood mononuclear cells (PBMC) with a pIC50 value of 8.1. STING modulator-5 is a antagonist of THP-1 cells, it can be used for immunological disease research.
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- No. CAS: 2305940-22-9
- Fòrmula: C43H45F4N11O5
- Peso molecular:871.88
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
STING modulator-5 (4 hours) shows antagonistic effects to peripheral blood mononuclear cells (PBMC) with a pIC50 value of 8.1[1]. STING modulator-5 shows the binding potency to C-terminal domain (CTD) of human STING with a pIC50 value of 9.5 by the FRET Assay[1]. STING modulator-5 antagonizes THP-1 cells with a pIC50 value of 8.9[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2305940-22-9
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Peso molecular 871.88
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Fòrmula C43H45F4N11O5
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SMILES
CN(/C1=N\C(C2=CC(C)=NN2CC)=O)C3=CC=CC=C3N1CC(F)(F)C(F)(F)CN4C5=C(OCC6=CC=C(C=C6)OC)C=C(C(N)=O)C=C5N(/C4=N\C(C7=CC(C)=NN7CC)=O)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
STING modulator-5 Related Classifications
HY-148643 Related Classifications
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