T 588
T 588 is an orally active neuroprotective agent. T 588 can increase acetylcholine release from the frontal cortex and hippocampus and meliorate cognitive dysfunction. T 588 can protect cerebellar granule cells from glutamate neurotoxicity. T 588can be used for the research of neurological disease, such as Alzheimer's disease.
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- No. CAS: 142935-03-3
- Fòrmula: C16H24ClNO2S
- Peso molecular:329.89
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Wobbler mice (model of motoneuron disease (MND))[1]
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Dosage:3, 10 and 30 mg/kg
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Administration:Orally administration, daily for 4 weeks
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Result:Potentiated grip strength, attenuated forelimb contracture and increased the weight of the biceps muscles.
Retarded denervation muscle atrophy and elevated activities of choline acetyltransferase (ChAT) or lactate dehydrogenase in the biceps muscles.
Chemical Information
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No. CAS 142935-03-3
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Peso molecular 329.89
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Fòrmula C16H24ClNO2S
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SMILES
CCN(CC)CCOC[C@@H](C1=CC=C(SC=C2)C2=C1)O.Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)