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Referencia número: HY-P1696

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U 70714E

U 70714E is a Renin inhibitor with an IC₅₀ of 3.0 nM. U 70714E is used for the research of renin-related hypertension.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 114376-16-8
Fòrmula: C₆₆H₇₆N₁₂O₁₀
Peso molecular:1197.38

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

U 70714E Chemical Structure

No. CAS: 114376-16-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

U 70714E is a Renin inhibitor with an IC₅₀ of 3.0 nM. U 70714E is used for the research of renin-related hypertension^[1].

In Vitro

Cardiovascular Regulation

U 70714E potently inhibits plasma renin in vitro, with an IC₅₀ of 3.0 nM, which is 2700 times more potent than the reference compound RIP^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Research Protocol for Cardiovascular Diseases

Chemical Information

No. CAS 114376-16-8
Peso molecular 1197.38
Fòrmula C₆₆H₇₆N₁₂O₁₀
Sequence

Ac-Trp(formyl)-Pro-Phe-His-Phe(deoxy)-Phe-Val-Tyr-NH2
Sequence Shortening

Ac-Trp(formyl)-PFH-Phe(deoxy)-FVY-NH2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (283 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Epps DE, et al. Structure-conformation relationships of synthetic peptide inhibitors of human renin studied by resonance energy transfer and molecular modeling. International journal of peptide and protein research. 1988 Jan;31(1):22-34.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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