WAY-855
WAY-855 is an active compound.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 482373-29-5
- Fòrmula: C9H11NO4
- Peso molecular:197.19
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Chemical Information
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No. CAS 482373-29-5
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Peso molecular 197.19
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Fòrmula C9H11NO4
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SMILES
OC([C@@]12[C@@]3([H])[C@]1([H])C[C@@]([C@]3(N)C(O)=O)([H])C2)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvente y solubilidad
DMSO : 230 mg/mL (1166.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5.75 mg/mL (29.16 mM); Clear solution
This protocol yields a clear solution of ≥ 5.75 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (57.5 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5.75 mg/mL (29.16 mM); Clear solution
This protocol yields a clear solution of ≥ 5.75 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (57.5 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureza y Documentación
Referencias
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.0713 mL | 25.3563 mL | 50.7125 mL | 126.7813 mL |
| 5 mM | 1.0143 mL | 5.0713 mL | 10.1425 mL | 25.3563 mL | |
| 10 mM | 0.5071 mL | 2.5356 mL | 5.0713 mL | 12.6781 mL | |
| 15 mM | 0.3381 mL | 1.6904 mL | 3.3808 mL | 8.4521 mL | |
| 20 mM | 0.2536 mL | 1.2678 mL | 2.5356 mL | 6.3391 mL | |
| 25 mM | 0.2029 mL | 1.0143 mL | 2.0285 mL | 5.0713 mL | |
| 30 mM | 0.1690 mL | 0.8452 mL | 1.6904 mL | 4.2260 mL | |
| 40 mM | 0.1268 mL | 0.6339 mL | 1.2678 mL | 3.1695 mL | |
| 50 mM | 0.1014 mL | 0.5071 mL | 1.0143 mL | 2.5356 mL | |
| 60 mM | 0.0845 mL | 0.4226 mL | 0.8452 mL | 2.1130 mL | |
| 80 mM | 0.0634 mL | 0.3170 mL | 0.6339 mL | 1.5848 mL | |
| 100 mM | 0.0507 mL | 0.2536 mL | 0.5071 mL | 1.2678 mL |
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