XD23
XD23 is a potent osteosarcoma inhibitor that works by downregulating DKK1 and activating the WNT/β-catenin signaling pathway.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2806007-82-7
- Fòrmula: C22H26ClN7O3
- Peso molecular:471.94
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A-375 | IC50 |
5.2 μM
Compound: 14m
|
Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
|
[PMID: 35797896] |
| MCF7 | IC50 |
3.15 μM
Compound: 14m
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
|
[PMID: 35797896] |
| SK-HEP1 | IC50 |
2.04 μM
Compound: 14m
|
Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
|
[PMID: 35797896] |
| SK-MEL-2 | IC50 |
4.79 μM
Compound: 14m
|
Antiproliferative activity against human SK-MEL-2 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
Antiproliferative activity against human SK-MEL-2 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
|
[PMID: 35797896] |
Chemical Information
-
No. CAS 2806007-82-7
-
Peso molecular 471.94
-
Fòrmula C22H26ClN7O3
-
SMILES
ClC1=CC=CC(NC(CNC2=CC(N3CCN(C)CC3)=NC(N(C)C(N4C)=O)=C2C4=O)=O)=C1
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)