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Gefitinib impurity 5 

Cat. No.: HY-133779
Handling Instructions

Gefitinib impurity 5 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity.

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Gefitinib impurity 5 Chemical Structure

Gefitinib impurity 5 Chemical Structure

CAS No. : 199327-61-2

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Description

Gefitinib impurity 5 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity[1][2].

Molecular Weight

319.36

Formula

C₁₆H₂₁N₃O₄

CAS No.

199327-61-2

SMILES

O=C1NC=NC2=C1C=C(OCCCN3CCOCC3)C(OC)=C2

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Gefitinib impurity 5Gefitinib impurity5Gefitinib impurity-5OthersInhibitorinhibitorinhibit

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Gefitinib impurity 5
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