Mapre3 - microtubule-associated protein, RP/EB family, member 3 Gene

Also Known as EB2; EB3; RP3; EBF3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 100732

Summary

Enables microtubule plus-end binding activity. Involved in positive regulation of cyclin-dependent protein serine/threonine kinase activity and positive regulation of transcription, DNA-templated. Acts upstream of or within positive regulation of microtubule plus-end binding activity. Located in cytoplasm; microtubule plus-end; and midbody. Colocalizes with microtubule. Orthologous to human MAPRE3 (microtubule associated protein RP/EB family member 3). [provided by Alliance of Genome Resources, Apr 2022]

Mapre3 Products (2)

mRNA Protein Name
NM_001310516.1 NP_001297445.1 microtubule-associated protein RP/EB family member 3 isoform 2
NM_133350.2 NP_579928.1 microtubule-associated protein RP/EB family member 3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables microtubule binding IDA
IDA: Inferred from direct assay
17310996 MGI
enables microtubule plus-end binding IDA
IDA: Inferred from direct assay
16148041 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16148041 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
17310996 MGI
involved in positive regulation of cyclin-dependent protein serine/threonine kinase activity IMP
IMP: Inferred from mutant phenotype
17310996 MGI
acts upstream of or within positive regulation of microtubule plus-end binding IGI
IGI: Inferred from genetic interaction
16148041 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17310996 MGI
colocalizes with microtubule IDA
IDA: Inferred from direct assay
17310996 MGI
located in microtubule cytoskeleton IDA
IDA: Inferred from direct assay
17310996 MGI
located in microtubule plus-end IDA
IDA: Inferred from direct assay
24145165 MGI
located in midbody IDA
IDA: Inferred from direct assay
17310996 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

microtubule-associated protein RP/EB family member 3

  • EB1 protein family member 3

  • end-binding protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08139 MAPRE3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20568 Mapre3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27077 Mapre3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mapre3 NCBI NCBI:22924