Nupr1 - nuclear protein 1, transcriptional regulator Gene

Also Known as p8; Nupr1l1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 100912108

Summary

Predicted to enable several functions, including acetyltransferase activator activity; chromatin binding activity; and transcription coactivator activity. Involved in several processes, including negative regulation of DNA-binding transcription factor activity; negative regulation of autophagy; and regulation of apoptotic process. Predicted to be located in intercellular bridge; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be part of protein-DNA complex. Predicted to be active in nucleus. Orthologous to human NUPR1 (nuclear protein 1, transcriptional regulator). [provided by Alliance of Genome Resources, Apr 2022]

Nupr1 Products (1)

mRNA Protein Name
NM_053611.2 NP_446063.1 nuclear protein 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of DNA-binding transcription factor activity IMP
IMP: Inferred from mutant phenotype
20181828 RGD
involved in negative regulation of autophagy IMP
IMP: Inferred from mutant phenotype
20181828 RGD
involved in negative regulation of cardiac muscle cell apoptotic process IMP
IMP: Inferred from mutant phenotype
20181828 RGD
involved in positive regulation of intrinsic apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
27031958 RGD
involved in positive regulation of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
28694771 RGD
involved in regulation of autophagy IMP
IMP: Inferred from mutant phenotype
28694771 RGD
involved in regulation of response to endoplasmic reticulum stress IMP
IMP: Inferred from mutant phenotype
28694771 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear protein 1

  • candidate of metastasis 1

  • nuclear protein 1-like

  • nuclear protein, transcriptional regulator, 1

  • nuclear protein, transcriptional regulator, 1-like 1

  • nuclear proten 1

  • nuclear transcriptional regulator protein 1

  • protein p8

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0532A Trifluoperazine dihydrochloride 99.98% Unkown
HY-B0532 Trifluoperazine 99.87% Unkown
HY-B0532B Trifluoperazine dimaleate / Unkown

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-111838A ZZW-115 hydrochloride Inducer 98.09% Unkown
HY-111838 ZZW-115 Activator 99.88% Unkown
HY-RS09702 NUPR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-B0532AS Trifluoperazine-d3 dihydrochloride / Unkown
HY-RS17469 Nupr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23927 Nupr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nupr1 NCBI NCBI:26471