Txndc5 - thioredoxin domain containing 5 Gene

Also Known as ERp46; PC-TRP

Species: Mus musculus

Gene Type: protein coding
Gene ID: 105245

Summary

Predicted to enable protein disulfide isomerase activity. Predicted to be involved in apoptotic cell clearance. Located in endoplasmic reticulum lumen. Is expressed in several structures, including brain; immune system; intestine; male reproductive gland or organ; and urinary system. Orthologous to human TXNDC5 (thioredoxin domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]

Txndc5 Products (3)

mRNA Protein Name
NM_001289598.1 NP_001276527.1 thioredoxin domain-containing protein 5 isoform 2
NM_001289599.1 NP_001276528.1 thioredoxin domain-containing protein 5 isoform 3
NM_145367.4 NP_663342.3 thioredoxin domain-containing protein 5 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein disulfide isomerase activity IGI
IGI: Inferred from genetic interaction
12930873 MGI
enables protein-disulfide reductase activity IDA
IDA: Inferred from direct assay
14971039 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum lumen IDA
IDA: Inferred from direct assay
12930873 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thioredoxin domain-containing protein 5

  • ER protein 46

  • endoplasmic reticulum protein ERp46

  • endoplasmic reticulum resident protein 46

  • plasma cell-specific thioredoxin-related protein

  • thioredoxin-like protein p46

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-122895 E64FC26 98.48% Unkown
HY-112056 DIM-C-pPhCO2Me 99.47% Unkown
HY-122895A (E/Z)-E64FC26 99.80% Unkown
HY-RS15294 TXNDC5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17353 Txndc5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23807 Txndc5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Txndc5 NCBI NCBI:81567