Mpig6b - megakaryocyte and platelet inhibitory receptor G6b Gene

Also Known as G6b; Ng31; C6orf25

Species: Mus musculus

Gene Type: protein coding
Gene ID: 106722

Summary

Acts upstream of or within blood coagulation; integrin-mediated signaling pathway; and myeloid cell differentiation. Predicted to be located in several cellular components, including Golgi apparatus; endoplasmic reticulum; and nucleoplasm. Predicted to be active in plasma membrane. Orthologous to human MPIG6B (megakaryocyte and platelet inhibitory receptor G6b). [provided by Alliance of Genome Resources, Apr 2022]

Mpig6b Products (2)

mRNA Protein Name
NM_001033221.3 NP_001028393.1 megakaryocyte and platelet inhibitory receptor G6b isoform 2 precursor
NM_001191012.1 NP_001177941.1 megakaryocyte and platelet inhibitory receptor G6b isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23112346 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within blood coagulation IMP
IMP: Inferred from mutant phenotype
23112346 MGI
acts upstream of or within integrin-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
23112346 MGI
acts upstream of or within megakaryocyte development IMP
IMP: Inferred from mutant phenotype
23112346 MGI
acts upstream of or within platelet formation IGI
IGI: Inferred from genetic interaction
23112346 MGI
acts upstream of or within platelet formation IMP
IMP: Inferred from mutant phenotype
23112346 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

megakaryocyte and platelet inhibitory receptor G6b

  • ITIM-receptor G6b-B

  • immunoreceptor tyrosine-based inhibitory motif (ITIM) containing platelet receptor

  • protein G6b

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08615 MPIG6B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20180 Mpig6b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26684 Mpig6b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mpig6b NCBI NCBI:80739