Chd4 - chromodomain helicase DNA binding protein 4 Gene
Also Known as Mi-2beta; mKIAA4075; D6Ertd380e; 9530019N15Rik
Species: Mus musculus
Summary
Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; histone deacetylase binding activity; and transcription coregulator binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and terminal button organization. Predicted to act upstream of or within chromatin organization. Located in nucleus. Part of NuRD complex and protein-DNA complex. Is expressed in several structures, including alimentary system; branchial arch; cardiovascular system; genitourinary system; and nervous system. Orthologous to human CHD4 (chromodomain helicase DNA binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]
Chd4 Products (8)
| mRNA | Protein | Name |
|---|---|---|
| NM_001346610.2 | NP_001333539.1 | chromodomain-helicase-DNA-binding protein 4 isoform g |
| NM_001403592.1 | NP_001390521.1 | chromodomain-helicase-DNA-binding protein 4 isoform a |
| NM_001403593.1 | NP_001390522.1 | chromodomain-helicase-DNA-binding protein 4 isoform b |
| NM_001403594.1 | NP_001390523.1 | chromodomain-helicase-DNA-binding protein 4 isoform c |
| NM_001403595.1 | NP_001390524.1 | chromodomain-helicase-DNA-binding protein 4 isoform d |
| NM_001403596.1 | NP_001390525.1 | chromodomain-helicase-DNA-binding protein 4 isoform e |
| NM_001403597.1 | NP_001390526.1 | chromodomain-helicase-DNA-binding protein 4 isoform f |
| NM_001403598.1 | NP_001390527.1 | chromodomain-helicase-DNA-binding protein 4 isoform g |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables DNA-binding transcription factor binding |
IPI
IPI: Inferred from physical interaction
|
33795231 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
21532573 | MGI |
| enables transcription factor binding |
IPI
IPI: Inferred from physical interaction
|
15767674 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of NuRD complex |
IDA
IDA: Inferred from direct assay
|
22075476 | MGI |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
20720167 | MGI |
| part of protein-DNA complex |
IDA
IDA: Inferred from direct assay
|
21245044 | MGI |
| part of protein-containing complex |
IDA
IDA: Inferred from direct assay
|
19796622 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
chromodomain-helicase-DNA-binding protein 4 |
|