Edem2 - ER degradation enhancer, mannosidase alpha-like 2 Gene

Also Known as 9530090G24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 108687

Summary

Predicted to enable calcium ion binding activity and mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Involved in positive regulation of retrograde protein transport, ER to cytosol. Predicted to be located in endoplasmic reticulum. Orthologous to human EDEM2 (ER degradation enhancing alpha-mannosidase like protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Edem2 Products (1)

mRNA Protein Name
NM_145537.2 NP_663512.2 ER degradation-enhancing alpha-mannosidase-like protein 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24200403 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of retrograde protein transport, ER to cytosol IDA
IDA: Inferred from direct assay
24200403 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ER degradation-enhancing alpha-mannosidase-like protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04158 EDEM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20395 Edem2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26904 Edem2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Edem2 NCBI NCBI:55741