Rnf20 - ring finger protein 20 Gene

Also Known as mKIAA4116; 4833430L21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 109331

Summary

Enables chromatin binding activity. Acts upstream of or within histone ubiquitination and positive regulation of histone methylation. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of HULC complex and ubiquitin Ligase complex. Is expressed in several structures, including adrenal gland; central nervous system; eye; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in breast Cancer. Orthologous to human RNF20 (ring finger protein 20). [provided by Alliance of Genome Resources, Apr 2022]

Rnf20 Products (3)

mRNA Protein Name
NM_001163263.1 NP_001156735.1 E3 ubiquitin-protein ligase BRE1A isoform 1
NM_001356401.1 NP_001343330.1 E3 ubiquitin-protein ligase BRE1A isoform 2
NM_182999.2 NP_892044.1 E3 ubiquitin-protein ligase BRE1A isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
22252316 MGI
enables histone H2B C-terminal K residue ubiquitin ligase activity IMP
IMP: Inferred from mutant phenotype
22252316 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22252316 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase BRE1A

  • BRE1-A

  • RING-type E3 ubiquitin transferase BRE1A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12075 RNF20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20095 Rnf20 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26598 Rnf20 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnf20 NCBI NCBI:56254