DTD2 - D-aminoacyl-tRNA deacylase 2 Gene

Also Known as ATD; C14orf126

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 112487

About DTD2

This gene has 3 transcripts (splice variants), 250 orthologues and 1 paralogue. Ubiquitous expression in fat (RPKM 6.7), brain (RPKM 4.9) and 25 other tissues.

Summary

Enables Ala-tRNA(Thr) hydrolase activity. Involved in aminoacyl-tRNA metabolism involved in translational fidelity. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

DTD2 Products (1)

mRNA Protein Name
NM_080664.3 NP_542395.1 D-aminoacyl-tRNA deacylase 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables Ala-tRNA(Thr) hydrolase activity IDA
IDA: Inferred from direct assay
29410408 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
22939629 GOA
Biological Process GO Annotation Evidence References Source
involved in aminoacyl-tRNA metabolism involved in translational fidelity IDA
IDA: Inferred from direct assay
29410408 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DTD2 Protein Structure

Tyr_Deacylase

Tyr_Deacylase: D-Tyr-tRNA(Tyr) deacylase (11 - 168)

  • 0
  • 100
  • 168 a.a.
Protein Preferred Names Protein Names

D-aminoacyl-tRNA deacylase 2

  • D-tyrosyl-tRNA deacylase 2 (putative)

Related Diseases

Diseases Alias
Frontometaphyseal Dysplasia 1

  • FMD1

  • Fmd
Frontometaphyseal Dysplasia

  • Fmd

  • Dysplasia, Frontometaphyseal
Otopalatodigital Syndrome Spectrum Disorder

  • Opd Spectrum Disorder

  • Opsd

  • Fronto-Otopalatodigital Osteodysplasia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04032 DTD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris DTD2 VGNC VGNC:97190
Rattus norvegicus DTD2 RGD RGD:1309138
Mus musculus DTD2 MGD MGI:1923485
Macaca mulatta DTD2 VGNC VGNC:108294
Felis catus DTD2 VGNC VGNC:80984
Others DTD2 NCBI