Gsto1 - glutathione S-transferase omega 1 Gene

Also Known as SPG-R

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114846

Summary

Enables glutathione dehydrogenase (ascorbate) activity. Involved in L-ascorbic acid biosynthetic process. Located in several cellular components, including cell body; myelin sheath; and nuclear membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease and Parkinson's disease. Orthologous to human GSTO1 (Glutathione S-transferase omega 1). [provided by Alliance of Genome Resources, Apr 2022]

Gsto1 Products (1)

mRNA Protein Name
NM_001007602.1 NP_001007603.1 glutathione S-transferase omega-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables glutathione dehydrogenase (ascorbate) activity IDA
IDA: Inferred from direct assay
9786866 RGD
Biological Process GO Annotation Evidence References Source
involved in L-ascorbic acid biosynthetic process IMP
IMP: Inferred from mutant phenotype
9786866 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
11311527 RGD
located in basement membrane IDA
IDA: Inferred from direct assay
11311527 RGD
located in cell body IDA
IDA: Inferred from direct assay
11311527 RGD
located in nuclear membrane IDA
IDA: Inferred from direct assay
11311527 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutathione S-transferase omega-1

  • GSTO 1-1

  • GSTO-1

  • MMA(V) reductase

  • S-(Phenacyl)glutathione reductase

  • glutathione S-transferase omega 1-1

  • glutathione-dependent dehydroascorbate reductase

  • monomethylarsonic acid reductase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-111530 GSTO1-IN-1 Inhibitor 99.11% Unkown
HY-115674 ML175 99.37% Unkown
HY-161876 GSTO1-IN-2 Inhibitor / Unkown
HY-178261 KT53 Inhibitor / Unkown
HY-178372 GSTO1-IN-4 Inhibitor / Unkown
HY-179635 GSTO1-IN-6 Inhibitor / Unkown
HY-182059 GSTP1-IN-1 / Unkown
HY-RS05884 GSTO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W615446 GSTO1-IN-3 Inhibitor / Unkown
HY-177695 GSTO1-IN-5 Inhibitor / Unkown
HY-RS17464 Gsto1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23922 Gsto1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gsto1 NCBI NCBI:9446