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Cat. No.: HY-161876

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GSTO1-IN-2

GSTO1-IN-2 (Compound B-9) is a dual covalent inhibitor of GSTO1/BTK with IC₅₀ values of 441 nM and 6.2 nM respectively.

For research use only. We do not sell to patients.

CAS No.: 3020776-77-3
Formula: C₃₀H₂₄N₈O₂
Molecular Weight:528.56

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

GSTO1-IN-2 Chemical Structure

CAS No.: 3020776-77-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

GSTO1-IN-2 (Compound B-9) is a dual covalent inhibitor of GSTO1/BTK with IC₅₀ values of 441 nM and 6.2 nM respectively^[1].

IC₅₀ & Target

IC50: 441 nM (GSTO1)^[1].
IC50: 6.2 nM (BTK)^[1].

Chemical Information

CAS No. 3020776-77-3
Molecular Weight 528.56
Formula C₃₀H₂₄N₈O₂
SMILES

N#CC1(C#N)C(C(N2C[C@H](N3N=C(C4=CC=C(OC5=CC=CC(C#C)=C5)C=C4)C6=C(N)N=CN=C63)CCC2)=O)C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liu Y, et al. Proteome-wide Ligand and Target Discovery by Using Strain-Enabled Cyclopropane Electrophiles[J]. Journal of the American Chemical Society, 2024. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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