Adora2b - adenosine A2b receptor Gene

Mus musculus

Also known as A2b; A2BR; A2BAR; AA2BR; ARA2B

Gene ID: 11541 | Gene type: protein coding

About Adora2b

Chromosome 11: 62,139,810-62,157,279 forward strand.GRCm39:CM001004.3

This gene has 1 transcript (splice variant), 200 orthologues, 3 paralogues and is associated with 37 phenotypes. Broad expression in duodenum adult (RPKM 18.), bladder adult (RPKM 15.8) and 2 other tissues.

Summary

Enables G protein-coupled receptor activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within several processes, including positive regulation of cGMP-mediated signaling; positive regulation of chronic inflammatory response to non-antigenic stimulus; and positive regulation of cytokine production. Located in Schaffer collateral - CA1 synapse; glutamatergic synapse; and plasma membrane. Is active in synapse. Is expressed in several structures, including cardiovascular system; central nervous system; eye; genitourinary system; and gut. Orthologous to human ADORA2B (adenosine A2b receptor). [provided by Alliance of Genome Resources, Apr 2022]

Adora2b Products(1)

mRNA	Protein	Name
NM_007413.4	NP_031439.2	adenosine receptor A2b

Adora2b Protein Structure

7tmA_Adenosine_R_A2B

0
100
200
300
332 a.a.

Protein Preferred Names

Protein Names

adenosine receptor A2b

A2b, Rs

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS00397	ADORA2B Human Pre-designed siRNA Set A	/	Unkown
HY-RS00398	Adora2b Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS00399	Adora2b Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Adora2b	NCBI	NCBI:136

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