CKS2 - CDC28 protein kinase regulatory subunit 2 Gene

Homo sapiens

Also known as CKSHS2

Gene ID: 1164 | Gene type: protein coding

About CKS2

Cytogenetic location: 9q22.2 Genomic coordinates (GRCh38): 9:89,311,195-89,316,703 (from NCBI)

This gene has 1 transcript (splice variant), 183 orthologues and 2 paralogues. Broad expression in testis (RPKM 88.8), bone marrow (RPKM 46.4) and 21 other tissues.

Summary

CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS2 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects specialized role for the encoded protein. [provided by RefSeq, Jul 2008]

CKS2 Products(1)

mRNA	Protein	Name
NM_001827.3	NP_001818.1	cyclin-dependent kinases regulatory subunit 2

CKS2 Protein Structure

CKS

0
79 a.a.

Protein Preferred Names

Protein Names

cyclin-dependent kinases regulatory subunit 2

CDC28 protein kinase 2

Related Diseases

Diseases

Alias

Coffin-Siris Syndrome 1

Coffin-Siris Syndrome	Fifth Digit Syndrome
Css	CSS1
Mrd12	Mental Retardation, Autosomal Dominant 12
Hhid	Dwarfism-Onychodysplasia
Hypertrichosis, Hyperkeratosis, Mental Retardation, And Distinctive Facial Features	Autosomal Dominant Mental Retardation 12
Short Stature-Onychodysplasia.	Intellectual Disability With Absent Fifth Fingernail And Terminal Phalanx
Mental Retardation With Hypoplastic Fifth Fingernails And Toenails	Short Stature-Onychodysplasia
Coffin-Siris Syndrome, Type 1	Mental Retardation, Autosomal Dominant, Type 12

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02743	CKS2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CKS2	MGD	MGI:1913447
Felis catus	CKS2	VGNC	VGNC:97381
Bos taurus	CKS2	VGNC	VGNC:27388
Rattus norvegicus	CKS2	RGD	RGD:1562047
Canis familiaris	CKS2	VGNC	VGNC:39293
Macaca mulatta	CKS2	VGNC	VGNC:104887
Others	CKS2	NCBI