Aplp2 - amyloid beta (A4) precursor-like protein 2 Gene

Also Known as CDEBP; APLP-2

Species: Mus musculus

Gene Type: protein coding

Gene ID: 11804

Summary

Predicted to enable identical protein binding activity. Acts upstream of or within several processes, including brain development; regulation of epidermal growth factor-activated receptor activity; and suckling behavior. Predicted to be located in nucleus. Is expressed in several structures, including axial musculature; compacted morula; lower urinary tract; submandibular gland primordium; and ventral grey horn. Orthologous to human APLP2 (amyloid beta precursor like protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Aplp2 Products (4)

mRNA	Protein	Name
NM_001102455.2	NP_001095925.1	amyloid beta precursor like protein 2 isoform a precursor
NM_001102456.2	NP_001095926.1	amyloid beta precursor like protein 2 isoform b precursor
NM_001357698.1	NP_001344627.1	amyloid beta precursor like protein 2 isoform d precursor
NM_009691.3	NP_033821.1	amyloid beta precursor like protein 2 isoform c precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	8894693	MGI

Biological Process GO Annotation	Evidence	References	Source
acts upstream of or within cholesterol metabolic process	IGI IGI: Inferred from genetic interaction	17920016	MGI
acts upstream of or within embryo development	IGI IGI: Inferred from genetic interaction	15689559	MGI
acts upstream of or within extracellular matrix organization	IGI IGI: Inferred from genetic interaction	15385965	MGI
acts upstream of or within forebrain development	IGI IGI: Inferred from genetic interaction	15385965	MGI
acts upstream of or within intracellular copper ion homeostasis	IMP IMP: Inferred from mutant phenotype	10526140	MGI
acts upstream of or within locomotory behavior	IGI IGI: Inferred from genetic interaction	9461064	MGI
acts upstream of or within mating behavior	IGI IGI: Inferred from genetic interaction	9461064	MGI
acts upstream of or within midbrain development	IGI IGI: Inferred from genetic interaction	15689559	MGI
acts upstream of or within neuromuscular process controlling balance	IGI IGI: Inferred from genetic interaction	9461064	MGI
acts upstream of or within regulation of epidermal growth factor-activated receptor activity	IGI IGI: Inferred from genetic interaction	17556541	MGI
acts upstream of or within regulation of protein binding	IGI IGI: Inferred from genetic interaction	17920016	MGI
acts upstream of or within suckling behavior	IGI IGI: Inferred from genetic interaction	9461064	MGI

Cellular Component GO Annotation	Evidence	References	Source
is active in spine apparatus	IDA IDA: Inferred from direct assay	28450540	MGI
is active in spine apparatus	IMP IMP: Inferred from mutant phenotype	28450540	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
amyloid beta precursor like protein 2 amyloid-like protein 2	CDE1-binding protein CDEBP CDEI box-binding protein amyloid protein homolog sperm membrane protein YWK-II

Protein Preferred Names

Protein Names

amyloid beta precursor like protein 2

amyloid-like protein 2

CDE1-binding protein CDEBP
CDEI box-binding protein
amyloid protein homolog
sperm membrane protein YWK-II

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00827	APLP2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20854	Aplp2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27369	Aplp2 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Aplp2	NCBI	NCBI:334