Barx2 - BarH-like homeobox 2 Gene

Also Known as Barx2b; 2310006E12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12023

Summary

Enables DNA-binding transcription factor activity; chromatin binding activity; and sequence-specific DNA binding activity. Acts upstream of or within cartilage condensation; myotube differentiation; and regulation of transcription by RNA polymerase II. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; limb; sensory organ; and skin. Orthologous to human BARX2 (BARX homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Barx2 Products (1)

mRNA Protein Name
NM_013800.2 NP_038828.2 homeobox protein BarH-like 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
15728386 MGI
enables DNA binding IGI
IGI: Inferred from genetic interaction
11278942 MGI
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
15800003 MGI
enables chromatin binding IDA
IDA: Inferred from direct assay
15728386 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11278942 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
15800003 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cartilage condensation IDA
IDA: Inferred from direct assay
15800003 MGI
acts upstream of or within cartilage condensation IMP
IMP: Inferred from mutant phenotype
15800003 MGI
acts upstream of or within catagen IMP
IMP: Inferred from mutant phenotype
15728386 MGI
acts upstream of or within myotube differentiation IMP
IMP: Inferred from mutant phenotype
12486129 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15728386 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15800003 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
12486129 MGI
acts upstream of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15800003 MGI
Cellular Component GO Annotation Evidence References Source
part of transcription regulator complex IDA
IDA: Inferred from direct assay
15728386 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein BarH-like 2

  • homeodomain transcription factor BARX2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01369 BARX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22403 Barx2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28927 Barx2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Barx2 NCBI NCBI:8538