Ccna2 - cyclin A2 Gene

Also Known as Ccn1; Ccna; Cyca; Ccn-1; CycA2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12428

Summary

Enables protein kinase binding activity. Acts upstream of or within positive regulation of transcription, DNA-templated. Located in cytoplasm; female pronucleus; and male pronucleus. Part of cyclin A2-CDK2 complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Orthologous to human CCNA2 (cyclin A2). [provided by Alliance of Genome Resources, Apr 2022]

Ccna2 Products (1)

mRNA Protein Name
NM_009828.3 NP_033958.2 cyclin-A2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11331592 MGI
enables protein kinase binding IPI
IPI: Inferred from physical interaction
11981756 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of DNA-templated transcription IGI
IGI: Inferred from genetic interaction
16137671 MGI
acts upstream of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
16137671 MGI
acts upstream of or within positive regulation of DNA-templated transcription IGI
IGI: Inferred from genetic interaction
16137671 MGI
acts upstream of or within positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
16137671 MGI
Cellular Component GO Annotation Evidence References Source
part of cyclin A2-CDK1 complex IPI
IPI: Inferred from physical interaction
19592082 MGI
part of cyclin A2-CDK2 complex IDA
IDA: Inferred from direct assay
7739547 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
15159393 MGI
located in female pronucleus IDA
IDA: Inferred from direct assay
16137671 MGI
located in male pronucleus IDA
IDA: Inferred from direct assay
16137671 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15159393 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclin-A2

  • Cyclin A2 (Cyclin A)

  • cyclin-A

Ccna2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Ccna2 P51943 CDK2 Homo sapiens P24941
GMS
21565702
Cross
Ccna2 P51943 CDK2 Homo sapiens P24941
X-Ray Diffraction
21565702
Intra
Ccna2 P51943 Cdk1 Mus musculus P11440
Anti Bait CoIP
19592082
Intra
Ccna2 P51943 Cdk2 Mus musculus P97377
Anti Bait CoIP
19592082
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W097625 6-Methoxyflavone 99.73% Unkown
HY-RS02117 CCNA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174321 A2073 Inhibitor / Unkown
HY-RS18168 Ccna2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24642 Ccna2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccna2 NCBI NCBI:890