Ccnd3 - cyclin D3 Gene

Also Known as 9230106B05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12445

Summary

Enables cyclin-dependent protein serine/threonine kinase activity and protein kinase binding activity. Acts upstream of or within several processes, including T cell proliferation; negative regulation of transcription by RNA polymerase II; and regulation of Insulin Receptor signaling pathway. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; extraembryonic component; eye; and gonad. Orthologous to human CCND3 (cyclin D3). [provided by Alliance of Genome Resources, Apr 2022]

Ccnd3 Products (3)

mRNA Protein Name
NM_001081635.1 NP_001075104.1 G1/S-specific cyclin-D3
NM_001081636.1 NP_001075105.1 G1/S-specific cyclin-D3
NM_007632.2 NP_031658.1 G1/S-specific cyclin-D3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cyclin-dependent protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
12130539 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8033213 MGI
enables protein kinase binding IPI
IPI: Inferred from physical interaction
23109711 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within T cell proliferation IMP
IMP: Inferred from mutant phenotype
14706337 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
23109711 MGI
acts upstream of or within regulation of cell cycle IDA
IDA: Inferred from direct assay
11809706 MGI
acts upstream of or within regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
23109711 MGI
acts upstream of or within signal transduction IDA
IDA: Inferred from direct assay
12130539 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
21539824 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G1/S-specific cyclin-D3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-R04612 4o8G-miR-592 / Unkown
HY-RS02125 CCND3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19992 Ccnd3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26496 Ccnd3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccnd3 NCBI NCBI:896