Noct - nocturnin Gene

Also Known as Ccr4; Ccrn4l

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12457

Summary

Enables mRNA binding activity and poly(A)-specific ribonuclease activity. Involved in several processes, including negative regulation of osteoblast differentiation; positive regulation of fat cell differentiation; and regulation of gene expression. Acts upstream of or within P-body assembly; circadian rhythm; and deadenylation-dependent decapping of nuclear-transcribed mRNA. Located in P-body; nucleus; and perinuclear region of cytoplasm. Is expressed in 2-cell stage embryo; central nervous system; and retina. Orthologous to human NOCT (nocturnin). [provided by Alliance of Genome Resources, Apr 2022]

Noct Products (1)

mRNA Protein Name
NM_009834.2 NP_033964.1 nocturnin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mRNA binding IDA
IDA: Inferred from direct assay
20685873 MGI
enables poly(A)-specific ribonuclease activity IDA
IDA: Inferred from direct assay
17400819 MGI
enables poly(A)-specific ribonuclease activity IMP
IMP: Inferred from mutant phenotype
22073225 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18625844 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within P-body assembly IGI
IGI: Inferred from genetic interaction
18625844 MGI
involved in circadian regulation of gene expression IMP
IMP: Inferred from mutant phenotype
20685873 MGI
involved in circadian rhythm IEP
IEP: Inferred from expression pattern
20685873 MGI
acts upstream of or within deadenylation-dependent decapping of nuclear-transcribed mRNA IGI
IGI: Inferred from genetic interaction
18625844 MGI
involved in mRNA stabilization IMP
IMP: Inferred from mutant phenotype
22073225 MGI
involved in negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
20685873 MGI
involved in negative regulation of osteoblast differentiation IMP
IMP: Inferred from mutant phenotype
20498072 MGI
involved in positive regulation of fat cell differentiation IMP
IMP: Inferred from mutant phenotype
20498072 MGI
involved in regulation of circadian rhythm IMP
IMP: Inferred from mutant phenotype
22073225 MGI
involved in regulation of embryonic development IMP
IMP: Inferred from mutant phenotype
23449310 MGI
involved in response to lipopolysaccharide IDA
IDA: Inferred from direct assay
22073225 MGI
Cellular Component GO Annotation Evidence References Source
located in P-body IDA
IDA: Inferred from direct assay
18625844 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
20498072 MGI
located in nucleus IDA
IDA: Inferred from direct assay
23449310 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
20498072 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nocturnin

  • CCR4 carbon catabolite repression 4-like

  • CCR4 protein homolog

  • carbon catabolite repression 4 homolog

  • carbon catabolite repression 4-like protein

  • circadian deadenylase NOC

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09402 NOCT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22263 Noct Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28785 Noct Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Noct NCBI NCBI:25819