Cd79a - CD79A antigen (immunoglobulin-associated alpha) Gene

Also Known as Iga; Ly54; mb-1; Ly-54; Igalpha; Ig-alpha

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12518

Summary

Predicted to enable identical protein binding activity. Involved in B cell differentiation and B cell proliferation. Acts upstream of or within B cell receptor signaling pathway. Located in external side of plasma membrane; membrane raft; and multivesicular body. Part of B cell receptor complex. Is expressed in liver. Human ortholog(s) of this gene implicated in agammaglobulinemia. Orthologous to human CD79A (CD79a molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd79a Products (1)

mRNA Protein Name
NM_007655.4 NP_031681.2 B-cell antigen receptor complex-associated protein alpha chain precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
1373499 MGI
enables transmembrane signaling receptor activity IDA
IDA: Inferred from direct assay
1439759 MGI
Biological Process GO Annotation Evidence References Source
involved in B cell activation IMP
IMP: Inferred from mutant phenotype
16860757 MGI
involved in B cell differentiation IMP
IMP: Inferred from mutant phenotype
11514602 MGI
involved in B cell proliferation IMP
IMP: Inferred from mutant phenotype
16860757 MGI
acts upstream of or within B cell receptor signaling pathway IDA
IDA: Inferred from direct assay
1373499 MGI
involved in B cell receptor signaling pathway IDA
IDA: Inferred from direct assay
1439759 MGI
Cellular Component GO Annotation Evidence References Source
part of B cell receptor complex IDA
IDA: Inferred from direct assay
1373499 MGI
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
1373499 MGI
located in membrane raft IDA
IDA: Inferred from direct assay
10587346 MGI
located in multivesicular body IDA
IDA: Inferred from direct assay
11854359 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

B-cell antigen receptor complex-associated protein alpha chain

  • MB-1 membrane glycoprotein

  • membrane-bound immunoglobulin-associated protein

  • surface IgM-associated protein

Recombinant Cd79a Proteins

Cat. No. Product Name Accession Purity
HY-P75383 CD79A Protein, Mouse (HEK293, Fc) P11911 (L29-R137) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P75385 CD79 Protein, Mouse (HEK293, His) P11911 (L29-R137)&P15530 (V26-D158) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02267 CD79A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17824 Cd79a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24292 Cd79a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991932 Anti-CD79A Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd79a NCBI NCBI:973