Csk - c-src tyrosine kinase Gene

Also Known as p50CSK

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12988

Summary

Predicted to enable several functions, including enzyme binding activity; identical protein binding activity; and non-membrane spanning protein tyrosine kinase activity. Acts upstream of or within negative regulation of cell population proliferation. Located in cell-cell junction. Is expressed in several structures, including Peyer's patch; central nervous system; genitourinary system; gut; and liver and biliary system. Orthologous to human CSK (C-terminal Src kinase). [provided by Alliance of Genome Resources, Apr 2022]

Csk Products (6)

mRNA Protein Name
NM_001304761.2 NP_001291690.1 tyrosine-protein kinase CSK
NM_001411641.1 NP_001398570.1 tyrosine-protein kinase CSK
NM_001411642.1 NP_001398571.1 tyrosine-protein kinase CSK
NM_001411643.1 NP_001398572.1 tyrosine-protein kinase CSK
NM_001411644.1 NP_001398573.1 tyrosine-protein kinase CSK
NM_007783.4 NP_031809.2 tyrosine-protein kinase CSK

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12612075 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of cell population proliferation IGI
IGI: Inferred from genetic interaction
15861137 MGI
acts upstream of or within negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15861137 MGI
Cellular Component GO Annotation Evidence References Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
15861137 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tyrosine-protein kinase CSK

  • C-Src kinase

  • protein-tyrosine kinase MPK-2

Recombinant Csk Proteins

Cat. No. Product Name Accession Purity
HY-P72957 CSK Protein, Mouse (Active, sf9, His-GST) P41241 (M1-L450) ≥ 85%, as determined by reducing SDS-PAGE.
HY-P75322 CSK Protein, Mouse (sf9) P41241 (M1-L450) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-131669 Dasatinib metabolite M6 Inhibitor 99.39% Unkown
HY-137345 DB-3-291 Degrader 99.08% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Csk NCBI NCBI:1445