Vcan - versican Gene

Also Known as NG2; hdf; PG-M; Cspg2; DPEAAE; PG-M(V0); PG-M(V1); 9430051N09; 5430420N07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13003

Summary

Enables protein Phosphatase binding activity. Acts upstream of or within heart development and ureteric bud development. Located in extracellular matrix. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; heart; and jaw. Human ortholog(s) of this gene implicated in intracranial aneurysm. Orthologous to human VCAN (versican). [provided by Alliance of Genome Resources, Apr 2022]

Vcan Products (5)

mRNA Protein Name
NM_001081249.1 NP_001074718.1 versican core protein isoform 1 precursor
NM_001134474.1 NP_001127946.1 versican core protein isoform 3 precursor
NM_001134475.1 NP_001127947.1 versican core protein isoform 4 precursor
NM_019389.2 NP_062262.2 versican core protein isoform 2 precursor
NM_172955.1 NP_766543.1 versican core protein isoform 5 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein phosphatase binding IPI
IPI: Inferred from physical interaction
21976490 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
9758703 MGI
involved in ureteric bud development IEP
IEP: Inferred from expression pattern
16545622 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
14620382 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

versican core protein

  • PG-M core protein

  • chondroitin sulfate proteoglycan core protein 2

  • large fibroblast proteoglycan

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15619 VCAN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19652 Vcan Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26145 Vcan Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vcan NCBI NCBI:1462