Eif4a1 - eukaryotic translation initiation factor 4A1 Gene

Also Known as Eif4; Ddx2a; BM-010

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13681

Summary

Predicted to enable double-stranded RNA binding activity and translation initiation factor activity. Predicted to be involved in cytoplasmic translational initiation. Predicted to act upstream of or within translational initiation. Predicted to be located in cytoplasm. Is expressed in several structures, including central nervous system; liver; lung; ovary; and sensory organ. Orthologous to human EIF4A1 (eukaryotic translation initiation factor 4A1). [provided by Alliance of Genome Resources, Apr 2022]

Eif4a1 Products (2)

mRNA Protein Name
NM_001159375.1 NP_001152847.1 eukaryotic initiation factor 4A-I isoform 2
NM_144958.4 NP_659207.1 eukaryotic initiation factor 4A-I isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16541103 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eukaryotic initiation factor 4A-I

  • ATP-dependent RNA helicase eIF4A-1

  • eIF-4A-I

  • eIF4A-I

  • initiation factor eIF-4A long form

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (17)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-19560 SBI-0640756 Inhibitor 99.75% Unkown
HY-RS04277 EIF4EBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-176844 eIF4A-IN-1 intermediate / Unkown
HY-RS04270 EIF4A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04281 EIF4G1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-164524 SBI-0640726 Inhibitor / Unkown
HY-129768 CMLD012072 Inhibitor / Unkown
HY-129769 CMLD012073 Inhibitor / Unkown
HY-145240 eIF4E-IN-1 Inhibitor / Unkown
HY-176842 eIF4A-IN-1 Inhibitor / Unkown
HY-RS04280 EIF4ENIF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19254 Eif4g1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20153 Eif4a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20227 Eif4ebp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25743 Eif4g1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26657 Eif4a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26734 Eif4ebp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif4a1 NCBI NCBI:1973