SBI-0640726
SBI-0640726 is an eIF4G1 inhibitor with antiproliferative activity in melanoma. SBI-0640726 disrupts the eIF4F translation initiation complex by inhibiting AKT and NF-kB signaling pathways. SBI-0640726 inhibits the growth of NRAS and BRAF mutant melanoma in vitro.
For research use only. We do not sell to patients.
- CAS No.: 1321827-45-5
- Formula: C23H15ClN2O2
- Molecular Weight:386.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1321827-45-5
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Molecular Weight 386.83
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Formula C23H15ClN2O2
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SMILES
O=C(C1=C(C2=CC=CC=C2)C3=C(C=CC(Cl)=C3)NC1=O)/C=C/C4=CC=CC=N4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)