CRIP1 - cysteine rich protein 1 Gene

Also Known as CRHP; CRIP; CRP1; CRP-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1396

About CRIP1

Cytogenetic location: 14q32.33 Genomic coordinates (GRCh38): 14:105,486,886-105,488,947 (from NCBI)

This gene has 6 transcripts (splice variants), 124 orthologues and 20 paralogues. Broad expression in small intestine (RPKM 154.6), lung (RPKM 120.1) and 20 other tissues.

Summary

Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double Zinc Finger Protein family, members of which include cysteine- and glycine-rich protein-1 (CSRP1; MIM 123876), rhombotin-1 (RBTN1; MIM 186921), rhombotin-2 (RBTN2; MIM 180385), and rhombotin-3 (RBTN3; MIM 180386). CRIP may be involved in intestinal zinc transport (Hempe and Cousins, 1991 [PubMed 1946385]).[supplied by OMIM, Mar 2008]

CRIP1 Products (1)

mRNA Protein Name
NM_001311.5 NP_001302.1 cysteine-rich protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables peptide binding IDA
IDA: Inferred from direct assay
18670594 GOA
enables zinc ion binding IDA
IDA: Inferred from direct assay
9126610 GOA
Biological Process GO Annotation Evidence References Source
involved in cellular response to UV-B IDA
IDA: Inferred from direct assay
20415737 GOA
involved in cellular response to antibiotic IDA
IDA: Inferred from direct assay
20415737 GOA
involved in immune response IEP
IEP: Inferred from expression pattern
20415737 GOA
involved in intrinsic apoptotic signaling pathway in response to DNA damage IDA
IDA: Inferred from direct assay
20415737 GOA
involved in prostate gland stromal morphogenesis IEP
IEP: Inferred from expression pattern
9507743 GOA
involved in regulation of gene expression IEP
IEP: Inferred from expression pattern
7999070 GOA
involved in response to zinc ion IDA
IDA: Inferred from direct assay
7999070 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
9126610 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CRIP1 Protein Structure

LIM

LIM: LIM domain (4 - 60)

  • 0
  • 77 a.a.
Protein Preferred Names Protein Names

cysteine-rich protein 1

  • cysteine-rich heart protein

Related Diseases

Diseases Alias
Situs Inversus

  • Situs Inversus Viscerum

  • Laterality Sequence

  • Complete Transposition

  • Siv
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03175 CRIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02920 CNRIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19671 Crip1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26164 Crip1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CRIP1 MGD MGI:88501
Canis familiaris CRIP1 VGNC VGNC:50444
Rattus norvegicus CRIP1 RGD RGD:1597237
Felis catus CRIP1 VGNC VGNC:104381