Vegfd - vascular endothelial growth factor D Gene

Also Known as Figf; VEGF-D

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14205

Summary

This gene encodes a member of the vascular endothelial growth factor (VEGF) family that acts as a ligand for vascular endothelial growth factor receptor 3. Signalling through this protein is important for growth and development of endothelial and vascular tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]

Vegfd Products (6)

mRNA Protein Name
NM_001308489.2 NP_001295418.1 vascular endothelial growth factor D isoform VEGF-D326 preproprotein
NM_001410630.1 NP_001397559.1 vascular endothelial growth factor D isoform VEGF-D326 preproprotein
NM_001410631.1 NP_001397560.1 vascular endothelial growth factor D isoform 3 precursor
NM_001410632.1 NP_001397561.1 vascular endothelial growth factor D isoform 4
NM_001410633.1 NP_001397562.1 vascular endothelial growth factor D isoform 5
NM_010216.3 NP_034346.1 vascular endothelial growth factor D isoform VEGF-D358 preproprotein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables growth factor activity IDA
IDA: Inferred from direct assay
8876195 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
11279005 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11279005 MGI
enables vascular endothelial growth factor receptor 3 binding IDA
IDA: Inferred from direct assay
11279005 MGI
Biological Process GO Annotation Evidence References Source
involved in dopaminergic neuron differentiation IDA
IDA: Inferred from direct assay
22535492 MGI
acts upstream of or within fibroblast proliferation IDA
IDA: Inferred from direct assay
8876195 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
acts upstream of or within vascular endothelial growth factor receptor signaling pathway IGI
IGI: Inferred from genetic interaction
11574540 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
8876195 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
11574540 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vascular endothelial growth factor D

  • c-fos induced growth factor

Recombinant Vegfd Proteins

Cat. No. Product Name Accession Purity
HY-P72430 VEGF-D Protein, Mouse (HEK293, His) P97946 (F98-S206) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73474 VEGF-D Protein, Mouse (HEK293, Fc) P97946 (F98-S206) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15638 VEGFD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174507 Human VEGFD mRNA / Unkown
HY-RS18414 Vegfd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24895 Vegfd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P9920A Ramucirumab (anti-VEGFR) Antagonist 99.9% Unkown
HY-P991626 VGX200 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vegfd NCBI NCBI:2277