Fnta - farnesyltransferase, CAAX box, alpha Gene

Also Known as FTA

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14272

Summary

Enables acetylcholine receptor regulator activity; Protein Prenyltransferase activity; and receptor tyrosine kinase binding activity. Acts upstream of or within neurotransmitter receptor metabolic process. Predicted to be part of CAAX-protein geranylgeranyltransferase complex; microtubule associated complex; and protein farnesyltransferase complex. Predicted to be active in cytoplasm. Is expressed in several structures, including adipose tissue; alimentary system; brain; hemolymphoid system gland; and reproductive system. Orthologous to human FNTA (farnesyltransferase, CAAX box, alpha). [provided by Alliance of Genome Resources, Apr 2022]

Fnta Products (1)

mRNA Protein Name
NM_008033.4 NP_032059.1 protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables Rab geranylgeranyltransferase activity IDA
IDA: Inferred from direct assay
14622576 MGI
enables protein farnesyltransferase activity IDA
IDA: Inferred from direct assay
14622576 MGI
enables protein geranylgeranyltransferase activity IMP
IMP: Inferred from mutant phenotype
14622576 MGI
enables receptor tyrosine kinase binding IPI
IPI: Inferred from physical interaction
14622576 MGI
Biological Process GO Annotation Evidence References Source
involved in enzyme-linked receptor protein signaling pathway IDA
IDA: Inferred from direct assay
18848351 MGI
involved in enzyme-linked receptor protein signaling pathway IGI
IGI: Inferred from genetic interaction
8653787 MGI
involved in enzyme-linked receptor protein signaling pathway IMP
IMP: Inferred from mutant phenotype
14622576 MGI
involved in positive regulation of Rac protein signal transduction IMP
IMP: Inferred from mutant phenotype
14622576 MGI
involved in positive regulation of skeletal muscle acetylcholine-gated channel clustering IDA
IDA: Inferred from direct assay
18848351 MGI
involved in positive regulation of skeletal muscle acetylcholine-gated channel clustering IGI
IGI: Inferred from genetic interaction
8653787 MGI
involved in positive regulation of skeletal muscle acetylcholine-gated channel clustering IMP
IMP: Inferred from mutant phenotype
14622576 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

  • CAAX farnesyltransferase subunit alpha

  • FTase-alpha

  • GGTase-I-alpha

  • ras proteins prenyltransferase subunit alpha

  • type I protein geranyl-geranyltransferase subunit alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05025 FNTA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22173 Fnta Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28695 Fnta Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fnta NCBI NCBI:2339