HECTD2 - HECT domain E3 ubiquitin protein ligase 2 Gene

Homo sapiens

Gene ID: 143279 | Gene type: protein coding

About HECTD2

This gene has 6 transcripts (splice variants), 220 orthologues and 24 paralogues. Ubiquitous expression in prostate (RPKM 5.7), brain (RPKM 4.5) and 24 other tissues.

Summary

Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

HECTD2 Products(4)

mRNA	Protein	Name
NM_001284274.3	NP_001271203.2	probable E3 ubiquitin-protein ligase HECTD2 isoform c
NM_001348365.2	NP_001335294.1	probable E3 ubiquitin-protein ligase HECTD2 isoform d
NM_173497.4	NP_775768.4	probable E3 ubiquitin-protein ligase HECTD2 isoform b
NM_182765.6	NP_877497.4	probable E3 ubiquitin-protein ligase HECTD2 isoform a

HECTD2 Protein Structure

HECT

0
200
400
600
776 a.a.

Protein Preferred Names

Protein Names

probable E3 ubiquitin-protein ligase HECTD2

HECT domain containing E3 ubiquitin protein ligase 2

Related Diseases

Diseases

Alias

Brain Compression

Compression Of Brain

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-W062696	BC-1382	Inhibitor	99.53%	Unkown
HY-RS06108	HECTD2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	HECTD2	VGNC	VGNC:29801
Rattus norvegicus	HECTD2	RGD	RGD:1305536
Mus musculus	HECTD2	MGD	MGI:2442663
Canis familiaris	HECTD2	VGNC	VGNC:41643
Felis catus	HECTD2	VGNC	VGNC:62783
Macaca mulatta	HECTD2	VGNC	VGNC:73246

Name
Email *

	Sorry, but the email address you supplied was invalid.