HECTD2 - HECT domain E3 ubiquitin protein ligase 2 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 143279

About HECTD2

This gene has 6 transcripts (splice variants), 220 orthologues and 24 paralogues. Ubiquitous expression in prostate (RPKM 5.7), brain (RPKM 4.5) and 24 other tissues.

Summary

Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

HECTD2 Products (4)

mRNA Protein Name
NM_001284274.3 NP_001271203.2 probable E3 ubiquitin-protein ligase HECTD2 isoform c
NM_001348365.2 NP_001335294.1 probable E3 ubiquitin-protein ligase HECTD2 isoform d
NM_173497.4 NP_775768.4 probable E3 ubiquitin-protein ligase HECTD2 isoform b
NM_182765.6 NP_877497.4 probable E3 ubiquitin-protein ligase HECTD2 isoform a

HECTD2 Protein Structure

HECT

HECT: HECT-domain (ubiquitin-transferase) (467 - 775)

  • 0
  • 200
  • 400
  • 600
  • 776 a.a.
Protein Preferred Names Protein Names

probable E3 ubiquitin-protein ligase HECTD2

  • HECT domain containing E3 ubiquitin protein ligase 2

Related Diseases

Diseases Alias
Brain Compression

  • Compression Of Brain
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W062696 BC-1382 Inhibitor 99.36% Unkown
HY-RS06108 HECTD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17923 Hectd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24393 Hectd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus HECTD2 VGNC VGNC:29801
Rattus norvegicus HECTD2 RGD RGD:1305536
Mus musculus HECTD2 MGD MGI:2442663
Canis familiaris HECTD2 VGNC VGNC:41643
Felis catus HECTD2 VGNC VGNC:62783
Macaca mulatta HECTD2 VGNC VGNC:73246
Others HECTD2 NCBI