Fut7 - fucosyltransferase 7 Gene

Also Known as FTVII; Fuc-TVII; FucT-VII

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14347

Summary

Predicted to enable 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity. Involved in leukocyte migration; regulation of cellular extravasation; and regulation of type IV hypersensitivity. Acts upstream of or within CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation and leukocyte migration involved in immune response. Predicted to be located in trans-Golgi network. Orthologous to human FUT7 (fucosyltransferase 7). [provided by Alliance of Genome Resources, Apr 2022]

Fut7 Products (7)

mRNA Protein Name
NM_001177366.1 NP_001170837.1 alpha-(1,3)-fucosyltransferase 7 isoform b
NM_001177367.1 NP_001170838.1 alpha-(1,3)-fucosyltransferase 7 isoform a
NM_001289453.1 NP_001276382.1 alpha-(1,3)-fucosyltransferase 7 isoform a
NM_001289454.1 NP_001276383.1 alpha-(1,3)-fucosyltransferase 7 isoform a
NM_001289455.1 NP_001276384.1 alpha-(1,3)-fucosyltransferase 7 isoform a
NM_001289456.1 NP_001276385.1 alpha-(1,3)-fucosyltransferase 7 isoform a
NM_013524.3 NP_038552.1 alpha-(1,3)-fucosyltransferase 7 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables alpha-(1->3)-fucosyltransferase activity IDA
IDA: Inferred from direct assay
11485743 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation IMP
IMP: Inferred from mutant phenotype
18573908 MGI
acts upstream of or within T cell migration IMP
IMP: Inferred from mutant phenotype
18573908 MGI
acts upstream of or within leukocyte migration involved in immune response IMP
IMP: Inferred from mutant phenotype
18573908 MGI
involved in leukocyte migration involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
11535629 MGI
involved in lymphocyte migration into lymph node IMP
IMP: Inferred from mutant phenotype
11485743 MGI
involved in lymphocyte migration into lymphoid organs IMP
IMP: Inferred from mutant phenotype
8752218 MGI
involved in positive regulation of leukocyte tethering or rolling IMP
IMP: Inferred from mutant phenotype
10894166 MGI
involved in positive regulation of neutrophil migration IMP
IMP: Inferred from mutant phenotype
11485743 MGI
involved in regulation of leukocyte adhesion to vascular endothelial cell IMP
IMP: Inferred from mutant phenotype
8752218 MGI
involved in regulation of neutrophil extravasation IMP
IMP: Inferred from mutant phenotype
8752218 MGI
involved in regulation of type IV hypersensitivity IMP
IMP: Inferred from mutant phenotype
11535629 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-(1,3)-fucosyltransferase 7

  • fucosyltransferase VII

  • galactoside 3-L-fucosyltransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70156 Fucosyltransferase 7 / Unkown
HY-RS05158 FUT7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18933 Fut7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25423 Fut7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fut7 NCBI NCBI:2529