Gnb3 - guanine nucleotide binding protein (G protein), beta 3 Gene
Also Known as Hg2d; Gnb-3
Species: Mus musculus
Summary
Predicted to enable GTPase binding activity; signaling receptor complex adaptor activity; and spectrin binding activity. Predicted to be involved in several processes, including cell volume homeostasis; regulation of fat cell differentiation; and regulation of lipid metabolic process. Located in dendrite. Part of heterotrimeric G-protein complex. Is expressed in several structures, including eye; ganglia; gut; liver; and spleen. Human ortholog(s) of this gene implicated in artery disease (multiple); congenital stationary night blindness 1H; familial hyperlipidemia; mental depression; and type 2 diabetes mellitus. Orthologous to human GNB3 (G protein subunit beta 3). [provided by Alliance of Genome Resources, Apr 2022]
Gnb3 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_013530.1 | NP_038558.1 | guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in dendrite |
IDA
IDA: Inferred from direct assay
|
12454992 | MGI |
| part of heterotrimeric G-protein complex |
IPI
IPI: Inferred from physical interaction
|
10570481 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS05548 | GNB3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS21351 | Gnb3 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS27870 | Gnb3 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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