Gnrhr - gonadotropin releasing hormone receptor Gene
Species: Mus musculus
About Gnrhr
This gene has 3 transcripts (splice variants), 241 orthologues, 16 paralogues and is associated with 65 phenotypes. Low expression observed in reference dataset.
Summary
Predicted to enable gonadotropin-releasing hormone receptor activity; growth hormone-releasing hormone receptor activity; and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway and negative regulation of cell population proliferation. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including adenohypophysis; jaw; mandibular process; and ovary. Used to study hypogonadotropic hypogonadism 7 with or without anosmia. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 7 with or without anosmia. Orthologous to human GNRHR (gonadotropin releasing hormone receptor). [provided by Alliance of Genome Resources, Apr 2022]
Gnrhr Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001310651.1 | NP_001297580.1 | gonadotropin-releasing hormone receptor isoform 2 |
| NM_010323.2 | NP_034453.1 | gonadotropin-releasing hormone receptor isoform 1 |
| NM_001310653.1 | NP_001297582.1 | gonadotropin-releasing hormone receptor isoform 3 |
Gnrhr Protein Structure
7tm_GPCRs: cl28897 (35 - 326)
7tm_GPCRs: cd14964 (37 - 66)
7tm_GPCRs: cd14964 (76 - 99)
7tm_GPCRs: cd14964 (114 - 136)
7tm_GPCRs: cd14964 (157 - 173)
7tm_GPCRs: cd14964 (207 - 230)
7tm_GPCRs: cd14964 (264 - 286)
7tm_GPCRs: cd14964 (300 - 325)
- 0
- 100
- 200
- 300
- 327 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
gonadotropin-releasing hormone receptor |
|