Gp1bb - glycoprotein Ib, beta polypeptide Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14724

Summary

Predicted to enable identical protein binding activity. Predicted to act upstream of or within cell adhesion. Predicted to be integral component of plasma membrane. Is expressed in central nervous system; heart; male reproductive gland or organ; retina; and yolk sac. Used to study Bernard-Soulier syndrome. Human ortholog(s) of this gene implicated in Bernard-Soulier syndrome. Orthologous to human GP1BB (glycoprotein Ib platelet subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Gp1bb Products (2)

mRNA Protein Name
NM_001001999.1 NP_001001999.1 platelet glycoprotein Ib beta chain isoform 1 precursor
NM_010327.2 NP_034457.1 platelet glycoprotein Ib beta chain isoform 2 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in blood coagulation IDA
IDA: Inferred from direct assay
18187573 MGI
involved in megakaryocyte development IMP
IMP: Inferred from mutant phenotype
18187573 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

platelet glycoprotein Ib beta chain

  • GP-Ib beta

  • GPIb-beta

  • GPIbB

Recombinant Gp1bb Proteins

Cat. No. Product Name Accession Purity
HY-P77686 CD42c/GP1BB Protein, Mouse (HEK293, Fc) P56400 (P27-C147) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05608 GP1BB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18280 Gp1bb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24758 Gp1bb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gp1bb NCBI NCBI:2812