Cmklr1 - chemerin chemokine-like receptor 1 Gene

Also Known as DEZ; Gpcr27; ChemR23; mcmklr1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14747

Summary

Predicted to enable adipokinetic hormone binding activity; adipokinetic hormone receptor activity; and transmembrane signaling receptor activity. Involved in negative regulation of interleukin-12 production; positive regulation of cold-induced thermogenesis; and positive regulation of fat cell differentiation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; lung; and uterus. Orthologous to human CMKLR1 (chemerin chemokine-like receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Cmklr1 Products (2)

mRNA Protein Name
NM_001359060.1 NP_001345989.1 chemerin-like receptor 1
NM_008153.3 NP_032179.1 chemerin-like receptor 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of interleukin-12 production IMP
IMP: Inferred from mutant phenotype
15753205 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
26972253 MGI
involved in positive regulation of fat cell differentiation IMP
IMP: Inferred from mutant phenotype
17635925 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chemerin-like receptor 1

chemokine-like receptor 1

  • G-protein coupled receptor 27

  • G-protein coupled receptor DEZ

  • chemerin receptor

  • chemokine receptor-like 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-138097 α-NETA ≥98.0% Unkown
HY-P1844A Chemerin-9 (149-157) TFA 98.41% Unkown
HY-156460 CMKLR1 antagonist 1 Antagonist 99.70% Unkown
HY-174140 VU0514009 Antagonist 99.53% Unkown
HY-P1844 Chemerin-9 (149-157) 99.57% Unkown
HY-RS02860 CMKLR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174139 CMKLR1 antagonist 2 Antagonist / Unkown
HY-RS16979 Cmklr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23422 Cmklr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cmklr1 NCBI NCBI:1240