2. Gene
  3. TAFA4 - TAFA chemokine like family member 4 Gene

TAFA4 - TAFA chemokine like family member 4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TAFA-4; FAM19A4

Gene ID: 151647 | Gene type: protein coding

About TAFA4

Cytogenetic location: 3p14.1 Genomic coordinates (GRCh38): 3:68,731,766-68,932,547 (from NCBI)

This gene has 3 transcripts (splice variants), 181 orthologues and 3 paralogues. Biased expression in adrenal (RPKM 8.7), gall bladder (RPKM 0.7) and 1 other tissue.

Summary

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011]

TAFA4 Products(2)

mRNA Protein Name
NM_001005527.3 NP_001005527.1 chemokine-like protein TAFA-4 precursor
NM_182522.5 NP_872328.1 chemokine-like protein TAFA-4 precursor

TAFA4 Protein Structure

TAFA

TAFA: TAFA family (49 - 138)

  • 0
  • 100
  • 140 a.a.
Protein Preferred Names Protein Names

chemokine-like protein TAFA-4

family with sequence similarity 19 (chemokine (C-C motif)-like), member A4

Recombinant TAFA4 Proteins

Cat. No. Product Name Accession Purity
HY-P71350 TAFA4 Protein, Human (His) Q96LR4 (S35-R140) ≥95%

Related Diseases

Diseases Alias
Osteogenesis Imperfecta, Type Xiii

Osteogenesis Imperfecta Type 13

OI13

Osteogenesis Imperfecta Type Xiii

Oi, Type Xiii

Osteogenesis Imperfecta 13

Oi Type Xiii

Oi-Xiii
Inflammatory Bowel Disease 9

IBD9
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14182 TAFA4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TAFA4 VGNC VGNC:78191
Mus musculus TAFA4 MGD MGI:2444563
Canis familiaris TAFA4 VGNC VGNC:40648
Rattus norvegicus TAFA4 RGD RGD:1597443
Felis catus TAFA4 VGNC VGNC:65940
Others TAFA4 NCBI