Il16 - interleukin 16 Gene

Also Known as mKIAA4048

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16170

Summary

Enables cytokine activity. Involved in cytokine-mediated signaling pathway. Acts upstream of or within several processes, including induction of positive chemotaxis; positive regulation of chemokine production; and positive regulation of neutrophil activation. Located in collagen-containing extracellular matrix. Is expressed in several structures, including foregut; jaw; limb; respiratory system; and vibrissa. Human ortholog(s) of this gene implicated in asthma and prostate Cancer. Orthologous to human IL16 (interleukin 16). [provided by Alliance of Genome Resources, Apr 2022]

Il16 Products (4)

mRNA Protein Name
NM_001360087.1 NP_001347016.1 pro-interleukin-16 isoform 1
NM_001360088.1 NP_001347017.1 pro-interleukin-16 isoform 3
NM_001360089.1 NP_001347018.1 pro-interleukin-16 isoform 4
NM_010551.4 NP_034681.2 pro-interleukin-16 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cytokine activity IDA
IDA: Inferred from direct assay
9637508 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9637508 MGI
Biological Process GO Annotation Evidence References Source
involved in cytokine-mediated signaling pathway IDA
IDA: Inferred from direct assay
30089723 MGI
acts upstream of or within induction of positive chemotaxis IDA
IDA: Inferred from direct assay
9637508 MGI
acts upstream of or within leukocyte chemotaxis IDA
IDA: Inferred from direct assay
9637508 MGI
acts upstream of or within positive regulation of chemokine production IDA
IDA: Inferred from direct assay
30089723 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: Inferred from direct assay
30089723 MGI
acts upstream of or within positive regulation of neutrophil activation IDA
IDA: Inferred from direct assay
30089723 MGI
Cellular Component GO Annotation Evidence References Source
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
9598300 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pro-interleukin-16

Recombinant Il16 Proteins

Cat. No. Product Name Accession Purity
HY-P71872 IL-16 Protein, Mouse O54824 (S1205-S1322) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P72590 IL-16 Protein, Mouse (His) O54824 (S1205-S1322) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P72590AF Animal-Free IL-16 Protein, Mouse (His) O54824-1 (H1197-S1322) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06694 IL16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174634 Human IL16 mRNA / Unkown
HY-RS18036 Il16 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24510 Il16 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il16 NCBI NCBI:3603