Il2rb - interleukin 2 receptor, beta chain Gene

Also Known as p70; CD122; IL15Rbeta; Il-2Rbeta; IL-15Rbeta; Il-2/15Rbeta

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16185

Summary

The interleukin 2 receptor is composed of alpha and beta subunits. The beta subunit encoded by this gene is very homologous to the human beta subunit and also shows structural similarity to other Cytokine Receptors. [provided by RefSeq, Jul 2008]

Il2rb Products (1)

mRNA Protein Name
NM_008368.4 NP_032394.1 interleukin-2 receptor subunit beta precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables interleukin-2 binding IPI
IPI: Inferred from physical interaction
8262055 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
20818394 MGI
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
8262055 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-2 receptor subunit beta

  • IL-15 receptor beta chain

  • IL-2 receptor beta chain

  • IL-2 receptor subunit beta

  • IL-2/15 receptor-beta

  • IL-2R subunit beta

  • IL-2RB

  • high affinity IL-2 receptor subunit beta

  • p70-75

Recombinant Il2rb Proteins

Cat. No. Product Name Accession Purity
HY-P71746 IL-2R beta/CD122 Protein, Mouse (P.pastoris, His) P16297 (A27-E240) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P72549 IL-2R beta/CD122 Protein, Mouse (HEK293, His) P16297 (A27-E240) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991279 Mik-Beta-1 Inhibitor ≥99.0% Phase 1

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06749 IL2RB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16278 Il2rb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17342 Il2rb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il2rb NCBI NCBI:3560