EID2 - EP300 interacting inhibitor of differentiation 2 Gene

Also Known as CRI2; EID-2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 163126

About EID2

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:39,538,707-39,540,161 (from NCBI)

This gene has 1 transcript (splice variant), 69 orthologues and 2 paralogues.

Summary

Enables SMAD binding activity. Involved in several processes, including negative regulation of transcription, DNA-templated; negative regulation of transforming growth factor beta receptor signaling pathway; and transmembrane receptor protein serine/threonine kinase signaling pathway. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

EID2 Products (1)

mRNA Protein Name
NM_153232.4 NP_694964.3 EP300-interacting inhibitor of differentiation 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables SMAD binding IDA
IDA: Inferred from direct assay
14612439 GOA
enables SMAD binding IPI
IPI: Inferred from physical interaction
14612439 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
15970276 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in negative regulation of SMAD protein signal transduction IDA
IDA: Inferred from direct assay
14612439 GOA
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
14612439 GOA
involved in negative regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: Inferred from direct assay
14612439 GOA
involved in regulation of cell population proliferation IDA
IDA: Inferred from direct assay
14612439 GOA
involved in transforming growth factor beta receptor complex assembly IDA
IDA: Inferred from direct assay
14612439 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

EP300-interacting inhibitor of differentiation 2

  • CREBBP/EP300 inhibitor 2

Related Diseases

Diseases Alias
Cutaneous Diphtheria

  • Diphtheria Wound Infection
Siberian Tick Typhus

  • North Asian Tick Typhus

  • Manchurian Typhus

  • North Asian Tick Fever

  • Rickettsia Sibirica Spotted Fever

  • Spotted Fever Group Rickettsiosis
Epidemic Pleurodynia

  • Bornholm Disease

  • Epidemic Myalgia

  • Pleurodynia, Epidemic

  • Devil'S Grip

  • Bamble Disease

  • Epidemic Pleurisy

  • Epidemic, Myositis

  • Dabney'S Grip

  • Epidemic Benign Dry Pleurisy

  • Epidemic Cervical Myalgia
Lymph Node Tuberculosis

  • King'S Evil

  • Scrofula

  • Tuberculous Adenitis

  • Tuberculous Lymphadenopathy

  • Tuberculosis, Lymph Node
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS04235 EID2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18755 Eid2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25242 Eid2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta EID2 VGNC VGNC:72129
Rattus norvegicus EID2 RGD RGD:1591322
Mus musculus EID2 MGD MGI:2681174
Others EID2 NCBI