Mc5r - melanocortin 5 receptor Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17203

About Mc5r

Chromosome 18: 68,470,575-68,475,517 forward strand.GRCm39:CM001011.3

This gene has 1 transcript (splice variant), 183 orthologues, 18 paralogues and is associated with 6 phenotypes. Broad expression in bladder adult (RPKM 1.6), mammary gland adult (RPKM 1.2) and 17 other tissues.

Summary

Predicted to enable hormone binding activity and Melanocortin Receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in skin. Orthologous to human MC5R (melanocortin 5 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Mc5r Products (1)

mRNA Protein Name
NM_013596.3 NP_038624.3 melanocortin receptor 5

Mc5r Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (36 - 305)

7tm_GPCRs

7tm_GPCRs: cd14964 (38 - 62)

7tm_GPCRs

7tm_GPCRs: cd14964 (71 - 93)

7tm_GPCRs

7tm_GPCRs: cd14964 (115 - 137)

7tm_GPCRs

7tm_GPCRs: cd14964 (160 - 176)

7tm_GPCRs

7tm_GPCRs: cd14964 (182 - 205)

7tm_GPCRs

7tm_GPCRs: cd14964 (236 - 258)

7tm_GPCRs

7tm_GPCRs: cd14964 (273 - 298)

  • 0
  • 100
  • 200
  • 300
  • 325 a.a.
Protein Preferred Names Protein Names

melanocortin receptor 5

  • MC5-R

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-107139 JNJ-10229570 Antagonist 98.0% Phase 2

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P0227 SHU 9119 99.83% Unkown
HY-P0097A Nonapeptide-1 acetate salt Antagonist 95.58% Unkown
HY-P0097 Nonapeptide-1 Antagonist 98.74% Unkown
HY-19870C Setmelanotide monoacetate Agonist 99.81% Unkown
HY-P11469 PG-901 Modulator 99.35% Unkown
HY-P4665 Ac-c[Cys-Glu-His-d-Phe-Arg-Trp-d-Cys]-Pro-Pro-Lys-Asp-NH2 Antagonist 98.14% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mc5r NCBI NCBI:4161